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Work Experience:

Instructor, Michael Smith Laboratories and Department of Microbiology and Immunology, University of British Columbia
Director, First Year Seminars in Science (SCIE113), Faculty of Science


http://www.michaelsmith.ubc.ca/faculty/fox/
http://www.microbiology.ubc.ca/
http://www.bioteach.ubc.ca/
http://science.ubc.ca/students/new/courses/113

As a faculty member with the educational facilities of the Michael Smith Laboratories, I’m involved in a wide variety of outreach programs that range from science education initiatives, to high school field trip programs, to interdisciplinary projects that bridge the Arts and the Sciences. At the University, I contribute to undergraduate teaching in the Departments of Microbiology and Immunology (MICB405: Bioinformatics), for the Faculty of Science (SCIE113:First Year Seminar in Science), in a cross listed course (PATH547/BIOL437/BOTA544/FRST503/PLNT540: Laboratory in Molecular Biology), and in the Faculty of Arts and Sciences (ASIC200: Global Issues in the Arts and Sciences). I also lecture in courses from Medical Genetics, Pathology, Food Nutrition and Health, Biology, as well as in the professional development workshops hosted by AMBL. Annually, I organize two major science education conferences, one aimed at high school teacher professional development and the other for high school students. I’m also actively involved in our popular field trip programs, which have garnered a strong reputation for excellence. With our broad mandate of engaging audiences with science, my role at AMBL often involves very creative and collaborative projects. For example, I’m one of four faculty and staff members involved in leading the Terry* project on campus, a joint initiative of the University of British Columbia’s Faculties of Arts and Science. I am also project lead for the UBC MIX project aimed at creating interdisciplinary connections in courses at UBC.

2010 Summer, Fall Semester, Course Coordinator, Curricula Development, Instructor for SCIE113: First Year Seminar in Science, Faculty of Science, University of British Columbia

Fall Semester 2010, Instructor for PATH547/BIOL437/BOTA544/FRST503/PLNT540: Laboratory in Molecular Biology, University of British Columbia.

Fall Semesters 2005, 2006, 2007, 2008, 2009 to present – Instructor for MICB405:Bioinformatics, Department of Microbiology and Immunology, University of British Columbia.

Spring Semesters 2008, 2009 – Instructor for ASIC 200: Global Issues in the Arts and Sciences, Faculty of Arts & Faculty of Science, University of British Columbia.

2006 to present – Core Faculty Member for Canadian Bioinformatics Workshops (involved as an instructor since 1999, see teaching activities for more detailed information).

2003 – 2007 – Head of Support and Training, Research Associate, UBC Bioinformatics Centre, University of British Columbia.

This teaching and leadership role involved developing and delivering bioinformatics user support and training initiatives at the centre, leading bioinformatics curricula development projects, contributing to management of centre, and supervising bioinformatics research projects.

1997 – 2002 – Ph.D. Graduate Student, University of British Columbia & University of Calgary
Supervised by Dr. Frank Jirik, with expertise in fields of genetics, immunology, molecular & cellular biology and biochemistry. Thesis title: Disruption of a single Pten allele augments the chemotactic response of B-lymphocytes to stromal cell derived factor-1 (SDF-1)

1997 – 1997 – BC Cancer Agency, University of British Columbia
Supervised by Dr. Frank Jirik, research project funded by BC Breast Cancer Initiative investigating the molecular mechanisms of DNA damage in an in vivo cancer model system.

1996 – 1997 – De Novo Enzyme Corporation, Simon Fraser University
Supervised by Dr. Thor Borgford, worked on establishing and maintaining a system for in vitro protein expression.

1996 – 1996 – Merck Frosst Centre for Therapeutic Research
Supervised by Dr. Sophie Roy, worked in the Biochemistry and Molecular Biology Department on several proteins involved in the regulation of apoptosis.

1996 – 1995 – Biomedical Research Center, University of British Columbia
Supervised by Dr. Frank Jirik, worked with a lambda phage based transgenic model to study DNA mutation in DNA repair deficient backgrounds.

Education:

2002 Ph.D. Genetics, University of British Columbia
2003 Bioinformatics: Writing Software for Genome Research, Cold Spring Harbor Laboratories
2002 Certificate in Bioinformatics, University of British Columbia
1997 B.Sc. Biochemistry, Simon Fraser University

Funded Grants and Proposals:

2010-2008 NSERC PromoScience Program, Natural Sciences and Engineering Research Council of Canada, AMBL Science Outreach Programs at the Michael Smith Laboratories, Principal Applicant
2010-2009 Teaching and Learning Enhancement Fund, University of British Columbia, UBC MIX Project – Creating Interdisciplinary Connections in Classrooms at UBC, Principal Applicant
2010-2009 Teaching and Learning Enhancement Fund, University of British Columbia, TEDx TERRY TALKS AND TERRY TALES – INTERDISCIPLINARY STUDENT JAM – Ideas that Inspire Action, Co-Principal Applicant
2010-2009 Teaching and Learning Enhancement Fund, University of British Columbia, University of British Columbia International Genetically Engineered Machines (iGEM) team, Co-Principal Applicant
2010-2009 Teaching and Learning Enhancement Fund, University of British Columbia, Building a Sustainable Let’s Talk Science Partnership Program, Co-Applicant
2009-2008 Teaching and Learning Enhancement Fund, University of British Columbia, TERRY TALKS – INTERDISCIPLINARY STUDENT JAM – Ideas that Inspire Action, Co-Principal Applicant
2009-2008 Teaching and Learning Enhancement Fund, University of British Columbia, University of British Columbia International Genetically Engineered Machines (iGEM) team, Co-Applicant 2006-2005 Teaching and Learning Enhancement Fund, University of British Columbia, Applied Workshops in Bioinformatics – Introducing Bioinformatics Earlier in Undergraduate Education at UBC, Principal Applicant
2005-2004 Teaching and Learning Enhancement Fund, University of British Columbia, Applied Workshops in Bioinformatics – Enabling Students to Use Bioinformatics, Co-Principal Applicant
2005 AMS Innovative Project Fund, University of British Columbia, Accessing Genome Information Using the Web – Hosting the Ensembl HelpDesk Workshop for Students at UBC, Principal Applicant
2004 AMS Innovative Project Fund, University of British Columbia, Hosting the NCBI Training Course in Bioinformatics at UBC, Principal Applicant

Scholarships and Awards:

2009 ASM/UNESCO Visiting Resource Person (VRP) Program, award in support of visit to Nigerian Institute for Oceanography and Marine Research, Lagos, Nigeria
2009 American Society for Microbiology, Early Career Travel Award, ASM Conference for Undergraduate Educators
2006 Teaching Portfolio Competition Award, Centre for Teaching & Academic Growth, UBC
2002 Canadian Institutes of Health Research Institute of Genetics, IG Short-Term Exchange Program
2002, 2001 Alberta Heritage Foundation for Medical Research, Post-Graduate Fellowship
2000, 1999, 1998, 1997 Natural Sciences and Engineering Research Council, Post-Graduate Fellowship
1995 Natural Sciences and Engineering Research Council, Industrial Research Award.
1995-1992 Simon Fraser University, Shrum Entrance Scholarship

Publications:
Brazas MD, Fox JA, Brown T, McMillan S, Ouellette BF. (2008) Keeping pace with the data: 2008 update for the Bioinformatics Links Directory. Nucleic Acids Research 36:W2-4.

Fox JA, McMillan S, Ouellette BF. (2007) Conducting research on the web: 2007 update for the
bioinformatics links directory. Nucleic Acids Research 35:W3-5.

Jon Nakane, Keddie Brown, Peter Danielson, Joanne Fox, Yas Shirazu, Donna Lee, Esther Abd-Elmessih, and David Ng. (2006) Home Molecular Genetics MAKE:07: Backyard Biology page 65

Fox JA, McMillan S, Campbell G, Ouellette BFF. (2006) A Compilation of Molecular Biology Web Servers: 2006 Update on the Bioinformatics Links Directory. Nucleic Acids Research 34:W3-5.

Marshall C, Fox JA, Butland S, Ouellette BFF, Brinkman F, Tibbits G. (2005). Phylogeny of Na+-Ca2+ Exchanger (NCX) genes from genomic data identifies new gene duplications and a new family member in fish species. Physiological Genomics 21:161-73.

Fox JA, Butland SL, McMillan S, Campbell G, Ouellette BFF. (2005) The Bioinformatics Links Directory: a compilation of molecular biology web servers. Nucleic Acids Research 33:W3-W24.

Fox JA, Ung K, Tanlimco SG, Jirik FR. (2002). Disruption of a single Pten allele augments the chemotactic response of B-lymphocytes to stromal cell derived factor-1 (SDF-1). Journal of Immunology 169: 49-54.

Andrew SE, Reitmair AH, Fox J, Hsiao L, Francis A, McKinnon M, Mak TW, Jirik FR. (1997). Base transitions dominate the mutational spectrum of a transgenic reporter gene in MSH2 deficient mice. Oncogene 15: 123-129.

Andrew SE, Pownall S, Fox J, Hsiao L, Hambleton J, Penney JE, Kohler SW, Jirik FR. (1996). A novel LacI transgenic mutation-detection system and its application to establish baseline mutation frequencies in the scid mouse. Mutation Research 357: 57-66.

Abstracts and Invited Presentations:

DNA, Genomes & Proteins – Hands-on Activities tell the story of the Central Dogma, Fox JA Featured Session, Catalyst 2010, BC Science Teachers’ Association Conference for K-12 Educators, March 25, 2010, Kelowna, BC

Humbolt-Kolleg-Osogbo International Conference on Biotechnology: Trends in the Advancement of Life Science Research and Development in Nigeria, Fox JA Invited Keynote, Bioinformatics in Life Sciences Research, August 2009, Ada, Nigeria.

Nigerian Institute for Oceanography and Marine Research, Fox JA Invited Speaker, Bioinformatics in Life Sciences Research, August 2009, Lagos, Nigeria.

Tools for Bringing Bioinformatics into Your Undergraduate Classrooms, Invited Presentation, 16th Annual ASM Conference for Undergraduate Educators, May 28-31, 2009, Colorado State University, Ft. Collins, CO (link)

Michael Smith Laboratories, Engaging Science & Genome BC Partner to Support High School Teachers, Keynote + Featured Workshop, Mitchell Odyssey Foundation Wild About Science Symposia ’08, Richmond, BC, 2008 (link)

RE-IMAGINING BIOLOGY: Science, Technology, and the Human Genome, Featured Session, Catalyst 2008 Conference, BC Science Teachers’ Association, Kelowna, BC, 2008 (link)

Platforms for Bioinformatics: Enabling Genetic Discovery, Invited Speaker, Department of Medical Genetics, University of Alberta, Edmonton, AB,, March 28th, 2007

Shah SP, He DYM, Sawkins J, Druce J, Quon G, Baluta D, Lett D, Zheng G, Xu T, Fox JA, Ouellette BFF (2004). Pegasys: Software for the analysis of large sets of biological sequences. Genome Informatics. Cold Spring Harbor Laboratories, USA.

Marshall CR, Fox JA, Butland SL, Ouellette BFF, Le HD, Hnatowich M, Hryshko LV, Tibbits GF (2004). Temperature Dependance of the Na+-Ca+ Exchanger (NCX); Combining Functional and Bioinformatics Approaches. Biophysical Society 48th Annual Meeting. Baltimore, USA.

Fox JA, Butland S, McMillan S, Campbell G, Ouellette BFF. Bioinformatics Core Facility: New Resources for CGDN Scientists. Canadian Genetic Diseases Network Annual Scientific Meeting, Collingwood, ON (CAN), May 27 – 30, 2004.

Fox JA, Butland S, McMillan S, Ouellette BFF. UBC Bioinformatics Centre: New Resources for CGDN Scientists. Canadian Genetic Diseases Network Annual Scientific Meeting, Kananaskis, AB (CAN), May 15 – 18, 2003.

Fox J, Ung K, Jirik FR. (2001). Disruption of a single Pten allele enhances the chemotactic response of B cells to stromal cell derived factor-1 (SDF-1). 11th International Conference on Second Messengers and Phosphoproteins. Melbourne, Australia.

Fox J, Zhang J, Matusik RJ, Jirik FR. (2000). Generating mice with prostate specific expression of Cre recombinase. HGM2000, The Human Genome Organization Annual General Meeting. Vancouver, Canada.

Andrew SE, Reitmair AH, Fox J, Hsiao L, Mak TW, Jirik FR. (1996). Analysis of spontaneous mutations in MSH2 ‘knock-out’ mice using a transgenic mutation detection system. Am. J. Hum. Genet. 59 Suppl; A264

Fox J, Matusik RJ, Jirik FR. (1999). Generating Mice with Prostate Specific Expression of Cre Recombinase. Canadian Genetic Diseases Network, Annual General Meeting. Toronto, Canada.

Fox J, Jirik FR. (1997) The development and utility of animal models in the Prostate Cancer Research Initiative. National Cancer Institute of Canada, Prostate Cancer Research Initiative Planning Workshop. Vancouver, Canada.

Andrew SE, Reitmair AH, Fox J, Hsiao L, Mak TW, Jirik FR. (1996). Analysis of spontaneous mutations in MSH2 ‘knockout’ mice using a transgenic mutation detection system. Gordon Conference – Mutagenesis. Plymouth, USA.

Fox J, Andrew SE, Hsiao L, Hambleton J, Reitmair AH, Jirik FR. (1996). Analysis of spontaneous mutations in MSH2 knockout mice using a transgenic mutation detection system. Transgenic Animals in Mutation Research, EMS Satellite Meeting. Victoria, Canada.

Hsiao L, Andrew SE, Fox J, Hambleton J, Jirik FR. (1996). Mutagenicity of menadione on rat embryonic fibroblasts using a selectable assay. Transgenic Animals in Mutation Research, EMS Satellite Meeting. Victoria, Canada.

Andrew SE, Reitmair AH, Fox J, Hsiao L, Mak TW, Jirik FR. (1996). Analysis of spontaneous mutations in MSH2 ‘knockout’ mice using a transgenic mutation detection system. Gordon Conference on DNA mutation. USA.

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